Hunter New England Cumulative Antibiogram Updates reflecting 2015 isolate data

Hot of the press – our updated antibiograms with commentaries – revised format.

Some take home messages from these analyses:

  1. Gentamicin retains excellent coverage of aerobic Gram negative bacteria and remains the best choice for empirical Gram negative cover, as reflected in the Australian Therapeutic Guidelines: Antibiotic recommendations.
  2. The proportion of non-urinary isolates of Staph. aureus that are MRSA is driven by outpatient presentations with skin and soft tissue infection and ranged between 14 and 23% across Hunter New England regions (table below). For that reason, it’s important to culture open skin infections for MRSA and use alternative treatment if an antibiotic is indicated and MRSA detected –   oral doxycycline or trimethoprim+sulphamethoxazole are suitable.

Percent MRSA

3. Tetracycline (doxycycline) retains high levels of activity against Streptococcus pneumoniae and Haemophilus influenzae. It is the recommended non-betalactam alternative in mild-moderate community-acquired pneumonia and in those patients with acute on COPD who meet criteria for treatment.

Cumulative antibiograms provide a summary of current bacterial antimicrobial susceptibility for key pathogens in urine and non-urine specimens. The antibiogram reports also include analyses of bloodstream  infections , community and healthcare -associated and key bacterial antibiotic resistances in such events.  Treatment recommendations based on Therapeutic Guidelines, Antibiotic, Edition 15, 2014 are included in each report.

One comment

  1. […] Local (HNE) cumulative antibiograms are available on this website and provide detailed information on susceptibility of S. aureus to other antibiotic classes, including the prevalence of MRSA  (resistance is by target site modification) across HNE locations – a summary of 2015 data is here. […]


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