Antibiograms and commentaries – 2021 data Hunter New England LHD

Provided by Dr Rob George, Pathology NSW, 11/10/22: 

Excerpt from HNELHD Cumulative Antibiograms 2021: John Hunter Hospital Commentary
Frequently isolated pathogens included: Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Haemophilus influenza, and Streptococcus pyogenes (Group A).

  • Staphylococcus aureus was frequently isolated from the samples collected at John Hunter Hospital. Isolates demonstrated high rates of susceptibility to flucloxacillin (82% susceptibility,c.f. 81% the previous year) as the recommended first line oral agent and cefalexin as the second line agent recommended for use in penicillin hypersensitivity. Isolates susceptible to flucloxacillin are considered susceptible to cefazolin. 18% of isolates were MRSA, c.f. 19% the previous year. First line oral agents for the treatment of Staphylococcus aureus demonstrated mixed rates of susceptibility (85% clindamycin susceptibility, 97% sulfamethoxazole and trimethoprim susceptibility, and 96% doxycycline susceptibility).
  • Pseudomonas aeruginosa can be a respiratory and skin coloniser, but also cause invasive infections. Isolates demonstrated 95% tobramycin susceptibility (c.f. 91% the previous year), 91%ceftazidime susceptibility (c.f. 87% the previous year), and 89% ciprofloxacin susceptibility (c.f. 84% the previous year).
  • A respiratory pathogen of note was Haemophilus influenzae. Isolates demonstrated 56%ampicillin susceptibility (c.f. 57% the previous year), 99% ceftriaxone susceptibility, and 76%amoxicillin and clavulanic acid susceptibility (c.f. 73% the previous year).
  • Streptococcus pyogenes (Group A) isolates demonstrated 100% benzylpenicillin susceptibility. This organism is frequently isolated from skin and soft tissue infections.
  • Streptococcus pneumoniae was another Gram-positive organism of note. Infective presentations vary, including respiratory, bacteraemia, and meningitis. 76% of isolates tested were susceptible to erythromycin, and 78% of isolates tested were susceptible to doxycycline. Penicillin and ceftriaxone/cefotaxime breakpoint determination is dependent on presentation type. Penicillin and ceftriaxone/cefotaxime MIC surveillance data was not available from OrgTRx.
  • Zero percent of Enterococcus faecalis isolates were vancomycin resistant, and 53% of Enterococcus faecium isolates were vancomycin resistant.


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