Inducing ceftriaxone-deficiency in hospitals: practical stewardship insights
Originally posted on AIMED – Let's talk about antibiotics:
2018 update! Just as relevant. Upside – Ceftriaxone and cefotaxime (third generation cephalosporins-TGC) are amongst the most important agents for directed therapy of infections due to Gram negative organisms that are resistant to ampicillin or cephazolin (a first generation cephalosporin), including Klebsiella pneumoniae . They penetrate the CSF…
Inducing ceftriaxone-deficiency in hospitals: practical stewardship insights
2018 update! Just as relevant. Upside – Ceftriaxone and cefotaxime (third generation cephalosporins-TGC) are amongst the most important agents for directed therapy of infections due to Gram negative organisms that are resistant to ampicillin or cephazolin (a first generation cephalosporin), including Klebsiella pneumoniae . They penetrate the CSF well, making them important agents for treatment of meningitis due to […]
Alternative recommended antibiotics to ceftriaxone by syndrome and bug
Ceftriaxone (a third generation cephalosporin-TGC) remains an overused agent in some of our (HNELHD) facilities. We aim to keep usage below 20 defined daily doses per 1000 patient-days (as is done at John Hunter Hospital for instance) to prevent adverse ecological impacts on resistance – increases in MRSA, VRE, multi-resistant Gram negatives and C. difficile are all associated […]
Is vitamin C3 (ceftriaxone) a good anxiolytic for prescribers faced with diagnostic uncertainty ?
The adult presented with 1 week of non-productive cough (yes, a good history was taken), and had no signs of sepsis other than fever. CRP moderately raised, CXR normal. The clinician documented a vague differential diagnosis and started vitamin C3 (ceftriaxone).
ACIPC presentation – VRE control update Nov 2021
How can we control VRE? Ferguson ACIPC 2021 Invited presentation to ACIPC Conference – the top 3 horizontal (standard) controls are: Hand hygiene by healthcare staff Environmental controls – REACH trial Antimicrobial stewardship – target piperacillin+tazobactam and ceftriaxone to reduce usage below 30 DDD/1000 patient-days. References https://www.mja.com.au/journal/2019/211/3/reduced-vre-and-mrsa-colonisation-and-infection-following-sustained-reduction Ferguson- VRE in hospitals – 2014 monograph https://www.publish.csiro.au/ma/MA14011 […]
AAW on AIMED: our top ten posts
Just in case you missed them, here are the top ten most visited posts we have published over the last year. Special thanks to our audience – we target local prescribers and pharmacists primarily. We also appreciate the interactions with our international audience!
AIMED - Let's talk about antibiotics 