Recurrent urinary tract infection in women – are antibiotics the answer?
What is the evidence? This interesting paper from 2010 discusses the natural history of UTI in women and distinguishes two conditions – the ‘urethral’ (or ‘dysuria/frequency’) syndrome’ (US) which affects a proportion of women with recurrent symptoms and many courses of treatment. It is known that US is a self-limited condition in a majority of patients. Some women are said to […]
AAW on AIMED: our top ten posts
Just in case you missed them, here are the top ten most visited posts we have published over the last year. Special thanks to our audience – we target local prescribers and pharmacists primarily. We also appreciate the interactions with our international audience!
“UTI” – Requiem for a Heavyweight – a landmark paper
A recent paper, “Urinary Tract Infection”-Requiem for a Heavyweight by Dr Thomas Finucaine skillfully unpacks many key issues, coupling this with a consideration of the emerging knowledge of the urinary microbiome and virome, suggesting that the term “UTI” might better be referred to as a “urinary dysbiosis”. The paper is worth a detailed read – here […]
Alternative recommended antibiotics to ceftriaxone by syndrome and bug
Ceftriaxone (a third generation cephalosporin-TGC) remains an overused agent in some of our (HNELHD) facilities. We aim to keep usage below 20 defined daily doses per 1000 patient-days (as is done at John Hunter Hospital for instance) to prevent adverse ecological impacts on resistance – increases in MRSA, VRE, multi-resistant Gram negatives and C. difficile are all associated […]
An everyday tragedy: treating asymptomatic bacteruria with antibiotics
Act 1 of a common tragedy that sets the scene for antibiotic resistance – an elderly female resident of a nursing home complains of minor dysuria or perhaps just has urine that appears cloudy or smelly. The nurse collects some urine and performs a urinalysis that shows presence of white cells and nitrite. The urine is sent […]