Recurrent urinary tract infection in women – are antibiotics the answer?

What is the evidence? This interesting paper from 2010 discusses the natural history of UTI in women and distinguishes two conditions – the ‘urethral’ (or ‘dysuria/frequency’) syndrome’ (US) which affects a proportion of women with recurrent symptoms and many courses of treatment.  It is known that US is a self-limited condition in a majority of patients.  Some women are said to […]

AAW on AIMED: our top ten posts

Just in case you missed them, here are the top ten most visited posts we have published over the last year. Special thanks to our audience – we target local prescribers and pharmacists primarily. We also appreciate the interactions with our international audience! 

“UTI” – Requiem for a Heavyweight – a landmark paper

A recent paper, “Urinary Tract Infection”-Requiem for a Heavyweight  by Dr Thomas Finucaine skillfully unpacks many key issues, coupling this with a consideration of the emerging knowledge of the urinary microbiome and virome, suggesting that the term “UTI” might better be referred to as a “urinary dysbiosis”.  The paper is worth a detailed read – here […]

Alternative recommended antibiotics to ceftriaxone by syndrome and bug

Ceftriaxone (a third generation cephalosporin-TGC)  remains an overused agent in some of our (HNELHD) facilities.  We aim to keep usage below 20 defined daily doses per 1000 patient-days (as is done at John Hunter Hospital for instance) to prevent adverse ecological impacts on resistance – increases in MRSA, VRE, multi-resistant Gram negatives and C. difficile are all associated […]

An everyday tragedy: treating asymptomatic bacteruria with antibiotics

Act 1 of a common tragedy that sets the scene for antibiotic resistance – an elderly female resident of a nursing home complains of minor dysuria or perhaps just has urine that appears cloudy or smelly. The nurse collects some urine and performs a urinalysis that shows presence of white cells and nitrite.  The urine is sent […]