How can we control VRE? Ferguson ACIPC 2021

Invited presentation to ACIPC Conference – the top 3 horizontal (standard) controls are:

1. Hand hygiene by healthcare staff
2. Environmental  controls – REACH trial
3. Antimicrobial stewardship – target piperacillin+tazobactam and ceftriaxone to reduce usage below 30 DDD/1000 patient-days.

References

• https://www.mja.com.au/journal/2019/211/3/reduced-vre-and-mrsa-colonisation-and-infection-following-sustained-reduction
• Ferguson- VRE in hospitals – 2014 monograph https://www.publish.csiro.au/ma/MA14011
• https://aimed.net.au/2017/10/17/acute-piperacillintazobactam-shortage-important-advice-jhh-and-hnelhd/
• https://aimed.net.au/2017/06/09/piperacillintazobactam-shortage-recommended-alternatives-hnelhd/
• https://aimed.net.au/2018/02/28/inducing-ceftriaxone-deficiency-in-hospitals-practical-stewardship-insights-2/
• Lopez-Lozano et al.  A nonlinear time-series analysis approach to identify thresholds in associations between population antibiotic use and rates of resistance https://www.nature.com/articles/s41564-019-0410-0