What are cumulative antibiograms ?

Antibiograms summarise local antimicrobial susceptibility in order to guide appropriate antimicrobial prescribing. Ideally they are updated annually by microbiology services to provide a current  picture of bacterial susceptibility and the local incidence of key sentinel resistant pathogens.

Antibiograms provide data on the collective susceptibility of major pathogens across relevant types of antibiotic, usually stratified by specimen source (urine, non-urine or bloodstream). See an example table below configured according to the Australian recommended format.

Under Australian recommendations, they also include information about local occurrences  of sentinel pathogens such as MRSA, VRE, MRGN (ESBL and CRE) and penicillin -resistant pneumococci. In Hunter New England, we stratify these by healthcare status, detailing community-associated isolates separately.

Commentaries that interpret the local antibiogram against national therapeutic guideline recommendations are important to include if the antibiograms are to be shared with clinicians.

Antibiograms hospitals inform local empirical therapy,  guidelines and assist with formulary management.

The technical aspects of their production are well described in the relevant CLSI standard and also within the Commission document referenced below.

References

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