Category AMS strategy

Updated overview of approaches to CRE treatment

Guest posting from Professors Josh Davis (Hunter New England Health) and Patrick Harris (UQ).  AMBLER CLASS Class A Class B Class D Key characteristic Serine group enzyme Metallo-betalactamase OXA-type Key example(s) KPC, GES IMP, NDM, VIM OXA-48. (OXA-181, OXA-232 emerging) Susceptiblity features R to all b-lactams R to all b-lactams except Aztreonam May harbour other […]

Antibiotic Awareness Week 2022 – short seminar links x4

Here are the presentations from our recent short AMS lectures for AAW!  AMS- Who the blood hell are ya? Holly Jordan Jordan AAW Nov22 Overview of AMS at JHH Shorter is Better.  Josh Davis Davis Nov22 AAW slides Shorter is better Choosing antibiotics wisely – who really needs ceftriaxone or pip/tazo? John Ferguson Ferguson AAW Nov22 […]

Chronic venous or dependency wound golden rules

Guest posting from Dr Nicole Organ, Vascular Surgeon, HNE LHD Golden rules Maintain lower limb skin integrity – trauma avoidance, protective routine skin care Treat acute lower limb wounds/skin tears aggressively to prevent chronicity – early use of wound compression Address modifiable risk factors – superficial venous disease, obesity, sedentary lifestyle, arterial disease Use simple […]

Antimicrobial stewardship during Covid-19

Guest posting from Mr Joe Hessell, Dr Gaetan Khim, and Mr Mona Kheng, DMDP Staff Members.  See also these recent PRIDA AMS lectures.  A high rate of antimicrobial prescribing has been recognized for those with symptoms of COVID-19, much of which is unnecessarily promoting antimicrobial resistance (AMR). Long after the pandemic subsides, AMR will continue […]

Why does our local CAP guideline differ from Australian Therapeutic Guidelines?

Kristi, Lorrae and Ayesha have recently joined as AIMED authors– welcome aboard. Here’s a posting from Kristi that unpacks the approach to community-acquired pneumonia (CAP) in Hunter New England Health, NSW.   In adults, the most common bacterial cause of community-acquired pneumonia (CAP) is Streptococcus pneumoniae. Other pathogens associated with CAP include Haemophilus influenzae and atypical’ […]

How long should that antibiotic course last?

Guest posting from Ms Kristi Kozierowski, AMS and ICU pharmacist, John Hunter Hospital, NSW, Australia. This is a useful evidence-based summary produced for AAW 2019 – Duration FINAL Kozierowski 2019.  Usage welcome with acknowledgement. References Shorter is better : evidence review by Brad Spellberg  

Antibiotic awareness week 2018 – what antibiotic are you??

What antibiotic are you?  Take this short quiz !   Above items are from Kristi Kozierowski (AMS Pharmacist at John Hunter Hospital). Thanks Kristi!  Key Messages (Australian Commission for Safety and Quality in Healthcare) Antibiotics are a precious resource that could be lost. Antibiotic resistance is happening now – it is a worldwide problem that affects human […]

Smartphone website for local guidelines including pneumonia (HNELHD)

The  Quality Use of Medicines smartphone-enabled website has been updated to include changes to hospital acquired pneumonia guidelines. With this site, you are only three clicks away from a treatment recommendation!  See below for the range of guidelines available. Note that whilst Therapeutic Guidelines: Antibiotic remains the main resource, HNE guidelines, where approved, take precedence- […]

Acute piperacillin+tazobactam shortage – important advice – JHH and HNELHD

Currently (still in Feb 2018) there is a worldwide shortage of piperacillin+tazobactam , an additional issue to the shortage earlier in 2017 . Appropriate substitutions – see – HNELHD advice (November 2017)  JHH_Pip_Taz_Fact_Sheet_Oct_2017 . This includes new dosage recommendations for IV amox+clavulanate for intra-abdominal infection (6 -hrly rather than 8- hrly dosing). For further advice, please contact the […]

Overuse => global shortage! Let’s conserve what piperacillin+tazobactam we have left

Piperacillin+tazobactam (Tazocin) is one of our most important broad spectrum agents and is in short supply. Please conserve it by avoiding use in these common situations: Uncomplicated biliary sepsis  (Use ampicillin+gentamicin(max 48hrs) OR if allergic, ceftriaxone) Urinary tract infection with sepsis (Use ampicillin+gentamicin(max 48 hrs) OR if allergic, ceftriaxone) Early onset (< 5d after admission) […]