Piperacillin+tazobactam (Tazocin) is one of our most important broad spectrum agents and is in short supply.
Please conserve it by avoiding use in these common situations:
- Uncomplicated biliary sepsis (Use ampicillin+gentamicin(max 48hrs) OR if allergic, ceftriaxone)
- Urinary tract infection with sepsis (Use ampicillin+gentamicin(max 48 hrs) OR if allergic, ceftriaxone)
- Early onset (< 5d after admission) ICU -associated pneumonia or ward onset hospital acquired pneumonia (any time period after admission) (Use augmentin oral/IV OR benzylpenicillin+gentamicin)
- Community acquired pneumonia (For moderate CAP, use benzylpenicillin+doxycycline, severe CAP- benpen+gentamicin_azithromycin)
Note: For late onset (> 5 days after admission) ICU-associated pneumonia use of piperacillin+tazobactam is appropriate in the HNELHD setting.