Author Archives: mdjkf

Cotrimoxazole increases risk of sudden death in patients receiving renin-AT inhibitors

Co-trimoxazole and sudden death in patients receiving inhibitors of renin-angiotensin system: population based study | The BMJ

Antibiotic resistance-a potent example of a ‘Tragedy of the Commons’

The Tragedy of the Commons by Garrett Hardin, 1968 was a seminal work. His central idea concerns ‘resources’ held in common, that degrade or diminish if left to the self interest of individuals.  He argues that the problems that arise with allocation and preservation of such resources cannot be solved by technical answers alone – most importantly, a change in attitudes and behaviour towards […]

Is that second course of antibiotics really necessary?

You’ve been given an antibiotic by your GP for a respiratory infection. The course goes for 4 days and you still feel unwell !  You return to your medico and he/she gives you another course.

Does completing the course reduce bacterial antibiotic resistance?

The notion that completing the course of an antibiotic reduces the emergence of bacterial resistance is not accepted anymore. From in vitro evidence, we know that prolonged exposure to antibiotic , particularly at low levels (as occurs for instance in the oropharynx of patients treated with most oral antibiotics) is a good way to breed bacteria […]