Tag Archives: aminoglycoside

Antibiotic classes – why so important to know about them?

The antibiotic knowledge survey of our new interns this week,  showed that many were confused about which class vancomycin (a glycopeptide) fell into (30% thought it was an aminoglycoside).  This is a potentially dangerous confusion as the dosing, side effects and monitoring all differ substantially between these classes: Aminoglycoside Glycopeptide Indicative agents Gentamicin Vancomycin Dosing […]

Vitamin A(minoglycoside): safe use of gentamicin – recommended dosing and monitoring

We rely on the aminoglycoside gentamicin for its rapid bactericidal and broad spectrum action against Gram negative aerobes like E. coli and Klebsiella species.  It’s safety margin is increased in sepsis – the volume of distribution expands. Ototoxicity and nephrotoxocity is almost always due to cumulative effects of prolonged dosing and is minimised through use of […]