Tag Archives: beta-lactam

Vitamin ‘C1’ – cefazolin, cephalexin and cephalothin unpacked

These so-called first generation cephalosporins (C1) remain important agents for skin, soft tissue and urinary tract infections due to susceptible organisms and for surgical prophylaxis.  Increases in community acquired MRSA in some regions may lead to a different empiric choice for skin/soft tissue infection (e.g. doxycycline or trimethoprim+sulphamethoxazole).  Local cumulative antibiograms should also be examined to […]

Antibiotic Treatment Strategies for Community-Acquired Pneumonia in Adults

There is limited evidence comparing different antibiotic treatment strategies for patients with clinically suspected community acquired pneumonia patients who are admitted to non-intensive care beds. A study of 2283 patients in the Netherlands has compared treatment outcomes between patients treated with beta-lactam monotherapy, beta-lactam-macrolide combination therapy and fluroquinolone monotherapy. In this study beta-lactam monotherapy was […]