Tag Archives: Clostridium difficile

Recurrent community-acquired Clostridium difficile infection (CDI) – what to do?

A call from a local GP last week – 53 year old woman who was given a course of oral amoxycillin+clavulanate for respiratory infection and then developed moderately¬†severe¬†enteritis associated with CT evidence of colitis. Stool testing for C. difficile toxin genes was positive, confirming a diagnosis of CDI. She responded to a 10 day course […]

New Australasian Guidelines for the treatment of C. difficile

New Australasian Society of Infectious Diseases guidelines for the treatment of Clostridium difficile have been published in the Internal Medicine Journal this month. The guidelines provide management advice for C. difficile in adults and children in both hospital and community settings.

Clostridium difficile – misconceptions about testing

Confine testing to symptomatic patients. Testing of patients with formed stools may generate false positives due to asymptomatic carriage of toxigenic strains. An unfortunate side effect of multiplex PCR stool assays, are that tests that are inappropriate to the clinical circumstance may be performed, generating false positives. Also test at-risk (i.e. antibiotic or ppi-exposed) symptomatic […]