Tag Archives: meropenem

Sparing meropenem 101: what alternatives exist for the treatment of ESBL-producers?

April 20, 2016 · by · in Antimicrobial, Hospital practice · 1 Comment

Guest post: Patrick Harris, Staff Specialist in Microbiology, Central Laboratory, Pathology Queensland, Brisbane In a previous post we looked at bacteria that produce AmpC-type beta-lactamases, such as Enterobacter spp.  Perhaps a more familiar, and increasingly common, problem is presented by species such as E. coli or K. pneumoniae, which have acquired extended-spectrum beta-lactamase enzymes (or ‘ESBLs’).  […]

Sparing meropenem 101 – treatment of ESCPM species and AmpC betalactamases unpacked

February 3, 2016 · by · in AMS strategy, Journal paper · 2 Comments

Guest post: Patrick Harris, Staff Specialist in Microbiology, Central Laboratory, Pathology Queensland, Brisbane Infectious disease and microbiology trainees diligently learn about organisms that have a type of broad-spectrum beta-lactamase (i.e. an enzyme that can inactivate betalactam antibiotics) called ‘AmpC’.  These enzymes are encoded by a gene that is usually located on the chromosome of many Gram-negative […]