Tag Archives: MRSA

Outpatient MRSA load reduction (eradication) instructions

Your recent pathology test showed that you are carrying a strain of resistant Staphylococcus aureus (MRSA) bacteria that occasionally can cause serious infection.  See also this NSW MRSA Fact sheet.    This treatment aims to completely remove the MRSA from your body. In about half of the people treated in this way, the MRSA remains undetectable for yearsand […]

Patient advice: recurrent staphylococcal infection

Recurrent staphylococcal infection:  Natural history Virulent (aggressive) strains of Staphylococcus aureus (including golden staph- MRSA) are responsible for recurrent skin and soft tissue infections (e.g. boils)in previously well individuals (children and adults). The infections may recur over many months. Eventually some degree of immunity develops and the episodes become less frequent. However episodes may continue to occur […]

Q2 Understanding antibiotic resistance and Staphylococcus aureus

Q2 in our JMO pre-test asked: “What is the main mechanism by which the bacterium Staphylococcus aureus becomes resistant to penicillin?” We gave alternatives enumerating basic mechanisms that micro-organisms use (often in combination) to become resistant to an antimicrobial agent (graphic below).   Production of penicillinase (i.e. inactivation by a type of beta-lactamase) was the correct answer– more […]

Treatment of boils – Oz GPs reluctant to rely on scalpelmycin rather than antibiotics

Are you following best practice in the management of boils or recurrent skin infection?  We’ve previously addressed this matter detailing a NEJM study that indicated that a majority of US doctors surveyed use incision and drainage only. This recent Australian study investigated treatment of community staphylococcal skin abscesses by GPs and showed that a majority do not follow […]

Essential clinical care of Staphylococcus aureus bloodstream infection (SAB)

201 cases of SAB were managed across Hunter New England Health last year. The overall 30 day all-cause mortality was 22% (30% in those patients 60 years or above).  Relapse of infection occurs in 2-10% of adult patients and may occur up to 3 months after the original bacteraemia. Relapse rates are reduced but not eliminated […]

GP HealthPathways released for recurrent Staph. infection, MRSA and MDRO

The HealthPathways site (based on a model from Christchurch, NZ) are used by our local General Practitioners and others to guide management of common syndromes and to provide guides to hospital-based  services.  New MRSA and MDRO (multi-drug-resistant organism) pathways provide guidance in keeping with MDRO management recommended across Hunter New England Health District . The Recurrent Staphylococcal Infection pathway includes […]

The World Health Organisation: Antimicrobial Resistance Factsheet

The WHO updated their antimicrobial resistance fact sheet in April 2015. Key facts from the publication are: Antimicrobial resistance threatens the effective prevention and treatment of an ever-increasing range of infections caused by bacteria, parasites, viruses and fungi. It is an increasingly serious threat to global public health that requires action across all government sectors […]

Surgical prophylaxis – updated HNE LHD guidelines just released

Internet link to these guidelines is here.. SUMMARY

A cautionary tale: High usage of topical fusidic acid and rapid clonal expansion of fusidic acid-resistant Staphylococcus aureus

Clinical Infectious Diseases 2014 New Zealand report Researchers from the University of Auckland report that New Zealand, has now developed world’s highest rates of MRSA to topical antibacterial agents.