Tag Archives: multi-resistant organisms

Carbapenemase-producing Gram negatives – what are treatment options?

Guest posting from Professor Josh Davis, Infectious Diseases, John Hunter Hospital, NSW and Menzies Institute , Darwin, Dr Patrick Harris , NHMRC Early Career Fellow at The University of Queensland Centre for Clinical Research (UQCCR) Carbapenemase-producing Enterobacterales (CPE),  Pseudomonas aeruginosa and Acinetobacter baumannii are usually resistant to most other antibiotics in addition to meropenem.  Treatment […]

The safe use of intraventricular colistin

Guest posting : Dr Jonathan Ash, Advanced training registrar, John Hunter Hospital. Ventriculitis is a rare but potentially disastrous complication of external ventricular drain placement, and with increasing rates of multi-drug resistant organisms, effective parenteral antibiotic choices are limited. Colistin has an established role in the treatment of infections caused by MDR Gram negatives, particularly […]

The post-antibiotic era: A case study

Published in the latest issue of the MJA is a case study of a Victorian patient diagnosed with a carbapenem-resistant Klebsiella pneumoniae. The patient, from rural Victoria, had no history or recent overseas travel and no hospital contact for the last 15 years. He was transferred to a metropolitan hospital for intensive care for severe […]

How did bacteria become resistant?

We all know that antibiotic resistance increases through improper use of antibiotics. With recent discoveries of bacteria containing antibiotic resistance genes in isolated tribes it would seem that bacteria have always been resistant- so why is it such a problem now?

Multi-resistant KPC-2 bacteria in Victoria – should we worry in NSW?

During a national conference in February this year, the rest of the country learnt about a serious outbreak of carbapenem resistant Klebsiella pneumoniae (KPC2 type, a form of CRE or carbapenem-resistant Enterobacteriaceae) that was detected first in 2012 and has mainly focused around one Melbourne hospital. Last week, the media told us not much more about the outbreak, including some […]

GP HealthPathways released for recurrent Staph. infection, MRSA and MDRO

The HealthPathways site (based on a model from Christchurch, NZ) are used by our local General Practitioners and others to guide management of common syndromes and to provide guides to hospital-based  services.  New MRSA and MDRO (multi-drug-resistant organism) pathways provide guidance in keeping with MDRO management recommended across Hunter New England Health District . The Recurrent Staphylococcal Infection pathway includes […]