Tag Archives: PKPD

Understanding Antibiotic Spectrum and Efficacy: A practical guide for JMOs

Guest posting: Dr Eliza Milliken, Infectious Diseases Physician, Clinical Pharmacology Fellow, Chair District Quality Use of Medicines, Hunter New England Health Key takeaways Antibiotics are selective chemotherapeutic agents—cytotoxic to bacteria, not humans Antibiotic efficacy is governed by a complex interplay of host pharmacokinetics and organism pharmacodynamics It’s not just about T>MIC or half-life—dosing needs context […]